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Pharmaceutical & Life Sciences

The facilities that
develop and manufacture
critical medicines.

GMP
GMP construction capability
IQ
IQ-documented delivery
EPC
EPC partnership model

Why We Build Pharmaceutical & Life Sciences

Ireland manufactures
medicines for the world

Nine of the world's ten largest pharmaceutical companies operate manufacturing sites in Ireland. The country produces over half of Europe's top-selling biologic medicines and is the largest net exporter of pharmaceuticals in the EU.

These facilities are in a constant cycle of development. New product lines, regulatory upgrades, campus expansion, and the shift from small molecule to biologics are generating a sustained pipeline of construction activity. From GMP manufacturing and cleanroom fit-out to live facility modifications and IQ-documented construction, Conroy delivers as principal contractor or as construction partner within EPC delivery teams.

The global shift from small molecule to large molecule production is concentrating in Ireland. New biologics manufacturing suites, cell and gene therapy facilities, and single-use process environments are driving demand for specialist construction.

Updated EU GMP Annex 1 requirements are driving a wave of facility upgrades across Ireland's pharmaceutical manufacturing base — cleanroom reclassification, HVAC upgrades, contamination control improvements, and documentation overhauls.

Established pharmaceutical campuses are expanding — new production buildings, utility infrastructure, warehouse capacity, and administration facilities built within operational sites where live production cannot be interrupted.

Pharmaceutical clients increasingly deliver through EPC partners or multi-contractor frameworks. The construction scope sits within a wider delivery programme — requiring a contractor who integrates with the project team rather than operating in isolation.

What We Build

Six facility types.
GMP as standard.

New-Build Manufacturing Facilities

Greenfield GMP manufacturing buildings — structural frame, process-grade finishes, utility infrastructure, and classified environments delivered as a single programme.

GMP Finishes Cleanroom Process Utilities
Cleanroom Shell & Fit-Out

Flush panel systems, hygienic linings, coved junctions, pressure-rated doorsets, and sealed penetrations — envelope integrity tested for each classified space.

ISO 14644 Pressure Cascade EU GMP Annex 1
Live Facility Modifications

Construction within operational GMP environments — shutdown planning, contamination control barriers, change control integration, and interface management with ongoing production.

Shutdown Planning Contamination Control Change Control
Warehouse & Cold Storage

Temperature-controlled warehousing, GDP-compliant cold chain infrastructure, and pharmaceutical-grade storage for raw materials, intermediates, and finished product.

GDP Compliant Temperature Mapping BMS Integration
Utility Buildings & Plantrooms

Process utility infrastructure — purified water, WFI, clean steam, compressed air, nitrogen — including equipment plinths, vibration isolation, and drainage systems.

WFI / PW Clean Steam HVAC Plantroom
Refurbishment & Repurposing

Upgrading existing facilities for new product lines, regulatory standard changes, or operational reconfiguration — including strip-out, re-qualification, and phased reoccupation.

Strip-Out Re-Qualification Phased Handover
Cleanroom construction — pharmaceutical manufacturing environment
GMP Built In.
Quality Documented.
Pharmaceutical & Life Sciences — cleanroom construction

What We Build — Technical Specification

The disciplines we manage
under one contract

Every discipline below is delivered under one contract — from structural frame to GMP finishes, MEP coordination to IQ documentation. Construction access, demarcation, and permit-to-work protocols are integrated into every discipline.

Structural & Civil Works
Base Build

RC frame, structural steel, foundations, piling, and reinforced slabs designed for heavy process equipment loadings. Vibration isolation pads and anti-vibration mounts integrated from design stage.

RC Frame Heavy Loadings Vibration Isolation
Architectural & GMP Finishes
Flush Panel / Epoxy

Flush panel systems, hygienic linings, coved junctions, epoxy finishes, and GMP-rated doorsets. Fire compartment integrity maintained throughout — penetrations managed through formal permit and documented reinstatement.

Flush Panels Epoxy Coatings Fire Compartmentation
Cleanroom Envelope & Pressure Integrity
ISO Classified

Pressure-rated doorsets, sealed penetrations, vision panels, pass-throughs, and airlocks. Pressure cascade management and construction-phase air sampling maintained at all classified interfaces.

Pressure Cascade Airlock Design Contamination Control
Mechanical & HVAC
GMP-Grade HVAC

AHU installation, ductwork, pipework, process cooling, and clean utility interfaces — coordinated within the master programme. All mechanical isolations managed through the facility's PTW system.

AHU / HVAC Process Cooling PTW Integrated
Electrical & Instrumentation
Classified Environment Electrical

LV distribution, lighting, fire detection, emergency lighting, and BMS interface — designed and installed to support the classified environment. All electrical isolations planned and authorised through the facility's isolation management system.

LV Distribution BMS Interface Isolation Managed
Process Utility Infrastructure
Clean Utilities

Purified water, WFI, clean steam, compressed air, nitrogen, and vacuum systems — equipment bases, vibration isolation, and full services coordination. Live system tie-ins managed as discrete controlled activities with isolation and recommissioning protocols.

WFI / PW Clean Steam Live Tie-Ins
IQ Documentation & Traceability
Progressive IQ

Progressive IQ records — material certificates, ITPs, inspection sign-offs, and NCR dispositions — captured as works proceed and structured for validation.

IQ Records Material Certs NCR Register
Contamination Control & Live Tie-Ins
Controlled Delivery

Physical containment barriers, pressure differential management, and live utility tie-ins — each managed as a discrete controlled activity with isolation and recommissioning protocols.

Containment Isolation Plans Permit to Work

How We Deliver

GMP integrated
from day one

Our delivery model integrates GMP requirements into construction methodology, programme, and documentation from the point of appointment — whether as principal contractor or as a construction partner within an EPC delivery team.

Programme developed with the client's validation team. Contamination control plan, construction methodology, and documentation requirements agreed before mobilisation. Cleanroom classification, pressure cascade design, and finish specifications locked at Stage 2.

Flush panel systems, cleanroom doorsets, AHU packages, and process utility equipment are procured early — before secondary packages are finalised. Lead times on these items govern the programme. We identify, price, and place orders during pre-construction so the critical path is protected from day one.

Physical containment barriers, personnel flow controls, and pressure differential management in place before construction commences adjacent to classified areas. Construction-phase air sampling where required by the client's quality team.

All modifications to live GMP areas managed under the client's change control process. Tie-ins to live utilities planned as discrete controlled activities with isolation and recommissioning protocols.

Construction records produced to IQ standard throughout — material certificates, ITPs, inspection sign-offs, and NCR dispositions. As-built data delivered in a format that supports OQ and PQ directly.

Critical Environment & GMP Delivery Approach
Life sciences construction facility
Site delivery — Pharmaceutical & Life Sciences

Start a Conversation

Your facility needs
GMP delivery expertise.

Whether you are a pharmaceutical manufacturer delivering directly, an EPC partner managing a wider programme, or a project team preparing a construction package — we'd welcome the opportunity to discuss your project.

Director Contact
James Conroy
Procurement
D&B / EPC Partner / Traditional
Appointment stage
RIAI/RIBA Stage 2 — or EPC mobilisation